Devil’s Claw

Nature’s solution for joint health

Ancient wisdom meets modern science for joint support

Devil’s claw is a herbaceous perennial with clinically demonstrated benefits for supporting joint health. Native to southern Africa, devil’s claw has a long history of traditional use and is extensively represented in pharmacopoeias around the world.¹ Today, several published clinical studies have demonstrated its ability to support joint health.² ³ ⁴
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Benefits

Bone health

Rising demand for natural joint health support

A poll carried out in late 2022 found that 70% of older U.S. adults experience joint concerns regularly.⁵ Meanwhile, even if they are not experiencing issues currently, 44% of global consumers say they would like to improve their lifestyle in general from food and drink or supplements that aid joint and bone health.⁶ Consumer demand has led the bone and joint supplements market to be valued at 13.6 billion USD in 2023 with 7.5% expected growth annually between 2024 and 2032.

Joint support

several clinical studies show improvement in joint health

Patented extract

with a high level of actives, up to 40% harpagosides by UV and 20% harpagoside by HPLC

A long history of traditional use

known for centuries for its joint health benefits

Sustainably sourced

responsibly and reliably sourced with full traceability from Southern Africa

Low dose

only 1 capsule of 200mg of devil’s claw 40% harpagosides by UV

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The science behind

Devil’s Claw

Joint health benefits backed by science

A number of clinical trials support the use of devil’s claw for its joint health supporting benefits. Devil’s claw has been shown to exhibit a soothing effect on joints. ² ³ ⁴

Devil’s claw contains several active compounds, of which harpagoside is the most researched. However, several_ in vitro_ studies have shown higher bioactivity of a complete extract as compared to isolated harpagoside and it is believed that the various bioactives contribute to the reported clinical effects in a synergistic manner. Its benefits are attributed to its ability to suppress the release of certain cytokines. ⁷ ⁸

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Devil’s Claw

responsible sourcing

Helping you build a sustainable future

At Givaudan, we are committed to sourcing all materials and services in a way that protects both people and the environment by 2030. In 2021, we joined and are still currently contributing to a project, co-financed by BMZ-German Development Cooperation (GIZ): BioInnovation Africa programme (BIA II), with the Namibian devil’s claw exporters association to make sure the wild collection of devil’s claw is carried out sustainably for both people and the environment.  

To do so, during the first phase of the project, GACP+ guidelines were developed (Good Agricultural Practices and Collection practices in addition to Access & Benefit Sharing compliance, the “+”). These guidelines formalised the good practices to be followed by devil’s claw harvesting communities and promoted and monitored by the main four exporters of Namibia. Key requirements such as traceability to collector, resource preservation practices and respect of re-growth periods between harvests, as well as the compliance with applicable regulations regarding permits and agreements between collectors, traditional communities and exporters, are laid out in these guidelines, which are now being tested during phase two of the project.

The quality of the roots collected is enhanced thanks to these best-in-class harvesting and post harvesting practices. In addition, the project ensures that our supply chains are fully compliant with the applicable Access and Benefit Sharing (ABS) regulations in place in Namibia.

The alignment, endorsement and implementation of these guidelines by the four main exporters of devil’s claw in Namibia is a key milestone for the sector to speak a common voice and ensure that ethical sourcing requirements are met, despite the complexity of the supply chain.

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A traditional botanical for joint health support

Devil’s Claw (Harpagophytum procumbens) is an herbaceous plant native to the arid, sandy steppes of the Kalahari Desert in Southern Africa. Named after the shape of its hooked fruit, the root of this perennial plant was used for centuries by indigenous communities.⁹ Today, several clinical studies have demonstrated that Devil’s Claw can support joint health.

Why formulate

with

Devil’s Claw

?

Devil’s Claw is ideal for a wide range of uses, including tablets, instant drinks and sticks, shots, syrups, gummies and powder mixes. The low 200 mg dose makes it ideal for single daily tablets and capsules.
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FAQs

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References

Devil’s Claw

The natural adaptogen backed by science

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Our Commitment

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References

Enhanced nutrition in any application

OatWell™ offers multiple functional benefits for food formulations, making it a versatile ingredient and allowing for fibre fortification in many applications, including bread, crackers, pastas, sweet baked goods and extruded snacks.

OatWell™ behaves as a natural stabiliser/emulsifier, making it an ideal ingredient for clean label strategies, while its high viscosity can deliver thickening properties. In applications such as bakery or processed meats, it exhibits water binding capacities, which hold potential for fat reduction. For classic applications, such as crackers and cereals, it can add a satisfying crisp.
11.4g
of OatWell™ BG28 delivers: 3g of oat beta glucan, 5.6g of dietary fibre and only 32Kcal

Designed for your formulation needs

The Oatwell™ range offers varying levels of total dietary fibre, oat beta-glucan and protein content, as well as different particle sizes. Its unique characteristics make it easy to incorporate in application while meeting taste and nutritional targets for a truly enjoyable consumer experience.

Baked goods

  • Easy to incorporate
  • Water binding capacity and moisture retention help extend shelf life
  • Can be mixed in binder syrup to provide thickness
  • High viscosity delivers thickening properties and texture
  • Enables some fat reduction in cakes
  • Improves overall nutritional profile

Extruded cereals / Snacks

  • Easy to incorporate
  • Excellent format to deliver high content of oat beta-glucan and fibre
  • Good expansion properties
  • Lighter, aerated and crispy texture
  • No colour impact
  • Improves overall nutritional profile

Pasta

  • Easy to incorporate
  • Water binding
  • Comparable texture to regular pasta
  • Improves overall nutritional profile

RTM Powders

  • Free flowing and easy to blend
  • Good dispersion
  • Can deliver added mouthfeel
  • Texture may add to perception of satiety
  • Improves overall nutritional profile

A little product for a lot of nutrition

Our OatWell™ Bran BG28 has over 50% total fibre and 28% beta-glucan. This beta-glucan is a powerful fibre and can help achieve different health claims around the globe. For example in the US, using the heart health claim requires delivering 3g of beta-glucan/day. 

Unique properties to deliver unmatched benefits from oats

For over 30 years, OatWell™ has been researched to develop innovative oat products. Much of our work has focused on proving the health benefits of oat beta-glucans in order to deliver premium value to our customers.

A unique nutritional profile

Generally considered healthier and more nutritious than the other main cereals, oats offer a full range of benefits in a single ingredient. OatWell™ can be provided in three different concentrations of beta-glucans, all delivering both soluble and insoluble fibres, along with an average of 21% - 23% protein.

A proprietary production process

OatWell™ uses a unique production process to fractionate the oat kernel into three product lines: beta-glucan products, oat flours, and oat oils. Our production process preserves the native structure of oat beta-glucans, retaining their high molecular weight during fractionation into oat brans with a high amount of beta-glucans.

The importance of high molecular weight

The molecular weight of oat beta-glucan is essential to delivering health benefits. OatWell™'s beta-glucan has a very high molecular weight (2000-2500 kDa as naturally found in oats), which contributes to its unique viscosity and thickening properties. This viscosity has an important impact on physiological functions, such as reducing blood cholesterol levels, moderating blood glucose and insulin levels, and potentially benefiting satiety.

Benefits of OatWell’s high molecular weight:

  • Ability to effectively reduce cholesterol and maintain healthy blood sugar levels compared to low molecular weight alternatives
  • High viscosity – thickening properties
  • Excellent water-binding properties
  • Potential to replace fat in product formulations

Unlocking the potential of dietary fibres and oat beta-glucan

Dietary fibre is an essential part of a healthy diet, promoting digestive health and providing a range of benefits that can help maintain overall wellbeing. Found in fruits, vegetables, grains, and legumes, dietary fibres are carbohydrates that cannot be digested by the body.

Nutrition Facts Label: FDA definition of “dietary fibre”

"non-digestible soluble and insoluble carbohydrates (with 3 or more monomeric units), and lignin that are intrinsic and intact in plants; isolated or synthetic non-digestible carbohydrates (with 3 or more monomeric units) determined by FDA to have physiological effects that are beneficial to human health."⁸

Soluble Fibers

Soluble fibres are dispersible in water. Fibres with high molecular weight, such as OatWell™, transform into a gel-like substance as they move through the digestive tract, where they are fermented by beneficial bacteria.⁹ This type of fibre is known to reduce cholesterol levels, particularly LDL (bad cholesterol)¹⁰, and manage blood glucose levels⁷ making it particularly beneficial for those concerned with heart health and healthy blood glucose. When soluble fibre, such as that found in Oatwell™, is digested by beneficial bacteria in the large intestine, it acts as a prebiotic.¹¹ As a result of digestion, short chain fatty acids (SCFAs) are released in the colon and serve as a nutrition source for the colon’s own cells.

Oat beta-glucans

One exceptional soluble fibre is beta-glucan, a natural, indigestible polysaccharide found in oats, barley, yeast, bacteria, algae, and mushrooms. Oats are particularly rich in beta-glucan, with concentrations ranging from 3-5% depending on the variety. Oat bran, produced by removing the starchy content of the grain, contains the highest concentration of beta-glucan, offering numerous health benefits for cardiovascular health⁵ ⁶, glycaemic response⁷ and the gut microbiome.⁴

Insoluble fibres

Insoluble fibres, on the other hand, do not dissolve in water as they pass through the digestive system. They help promote regular bowel movements, helping the stool pass more quickly through the intestines, which studies indicate is associated with a reduced risk of colorectal cancer.¹² By delivering both insoluble and soluble dietary fibres, including beta-glucans,¹³  OatWell™ helps meet consumer expectations for nutritious and delightful food experiences while promoting overall wellbeing. Embrace the power of these natural ingredients to create food experiences that truly resonate with today's health-conscious consumers.

Prebiotic support for the gut microbiome

Oat fibre contributes to improved gut health by increasing faecal bulk, but there’s more to the story. OatWell™ oat bran fibre has prebiotic effects, promoting the growth of beneficial bacteria. These bacteria produce short-chain fatty acids like butyrate and propionate, which have been associated with anti-inflammatory, and cholesterol-lowering properties.²⁰

What is a prebiotic?

Prebiotics are substrates that are selectively utilised by host microorganisms that confer a health benefit. Simply put, they are food for beneficial microbes that live in the human gut. These microbes can produce short chain fatty acids, which are considered beneficial compounds. Most prebiotics are dietary fibres, but not all dietary fibres are prebiotics. Many prebiotic fibres are soluble and some are insoluble.¹¹

The prebiotic effects of oat bran fibre have been validated through years of research. In a review by Malkki and Virtanen, they cite: “in the large bowel, soluble dietary fibre increases the fermentation activity, especially production of butyric acid, enhances growth and colonisation of some probiotic bacterial strains, increases production of microbial mass and thereby aids the removal of nitrogen via faeces. It also increases wet weight of stools, thereby alleviating constipation”.²¹

Research conducted on oat beta-glucan demonstrates that it meets three important criteria, confirming its status as a prebiotic fibre:¹ ²

  • helps produce Short Chain Fatty Acids (SCFAs): acetate, propionate and butyrate³
  • increases lactic acid as well as bifidobacteria and lactobacilli³
  • increases faecal bulk and promotes proper gut function⁴
By nurturing the gut microbiome, OatWell™ is an ideal ally for creating healthy and delightful food experiences that optimize wellbeing from within.
Disclaimer
This web page is intended to provide business-to-business education and information. Its purpose is not intended to communicate to end consumers. Ingredient information is for educational purposes only; specific ingredients are not intended to prevent, treat, mitigate or cure any disease states. This information is not intended to be used in final consumer products and any use or reference of the intellectual property of Givaudan in the final product may only be made with Givaudan’s prior written permission.

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