Lemon balm extract has been shown to improve mood by affecting stress levels and mild anxiety,² ⁹ in particular through the action of its rosmarinic acid on the gamma amino butyric acid (GABA) pathway.¹³ GABA is the primary inhibitory neurotransmitter in the human central nervous system,¹⁰ with low levels associated with mild anxiety.¹¹ Rosmarinic acid is a naturally occurring phenolic compound in lemon balm leaf¹² and a potent inhibitor of GABA transaminase (GABA-T). Inhibition of GABA-T increases GABA levels in the brain.¹³ Cyracos™ has a broad spectrum of actives, including a standardised level of >7% rosmarinic acid and >14% hydroxycinnamic acid, which are both natural polyphenolic compounds associated with effects on sleep and relaxation.¹⁴
In a prospective, single-center, open-label study in 2011, 20 adults diagnosed with mild to moderate anxiety and sleep disturbances consumed 300 mg of Cyracos™ twice a day for 15 days.²
Cyracos™ was found to significantly reduce (as compared to baseline):
Furthermore, clinical ratings revealed that 95% of the participants responded positively to Cyracos™ supplementation. The study also demonstrated that Cyracos™ was well tolerated, with no side effects. While the results of this small study are promising, more research is warranted.
“Traditionally used in herbal medicine as a sleep aid (in cases of restlessness or insomnia due to mental stress)”
“Traditionally used in herbal medicine to help promote sleep during periods of restlessness or insomnia due to mental stress”
“Traditionally used in herbal medicine to help reduce insomnia, a symptom of stress”
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